TMPRSS11B

Mammalian protein found in Homo sapiens
TMPRSS11B
Identifiers
AliasesTMPRSS11B, transmembrane protease, serine 11B, transmembrane serine protease 11B, HATL5
External IDsHomoloGene: 131255; GeneCards: TMPRSS11B; OMA:TMPRSS11B - orthologs
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for TMPRSS11B
Genomic location for TMPRSS11B
Band4q13.2Start68,226,653 bp[1]
End68,245,694 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • mucosa of pharynx

  • oral cavity

  • body of tongue

  • gums

  • gingival epithelium

  • superior surface of tongue

  • amniotic fluid

  • vagina

  • sperm

  • buccal mucosa cell
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • peptidase activity
  • hydrolase activity
  • serine-type peptidase activity
  • serine-type endopeptidase activity
Cellular component
  • integral component of plasma membrane
  • membrane
  • extracellular region
  • extracellular exosome
  • integral component of membrane
  • plasma membrane
Biological process
  • proteolysis
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

132724

n/a

Ensembl

ENSG00000185873

n/a

UniProt

Q86T26

n/a

RefSeq (mRNA)

NM_182502

n/a

RefSeq (protein)

NP_872308

n/a

Location (UCSC)Chr 4: 68.23 – 68.25 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Transmembrane protease, serine 11B is a protein that in humans is encoded by the TMPRSS11B gene. [3]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000185873 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Entrez Gene: Transmembrane protease, serine 11B". Retrieved 2017-04-03.

Further reading

  • Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, Arellano AR, Lumley T, Rice K, Iakoubova O, Luke MM, Young BA, Malloy MJ, Kane JP, Ellis SG, Tracy RP, Devlin JJ, Psaty BM (2008). "Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study". Arterioscler. Thromb. Vasc. Biol. 28 (1): 173–9. doi:10.1161/ATVBAHA.107.153981. PMC 2636623. PMID 17975119.
  • Luke MM, O'Meara ES, Rowland CM, Shiffman D, Bare LA, Arellano AR, Longstreth WT, Lumley T, Rice K, Tracy RP, Devlin JJ, Psaty BM (2009). "Gene variants associated with ischemic stroke: the cardiovascular health study". Stroke. 40 (2): 363–8. doi:10.1161/STROKEAHA.108.521328. PMC 2881155. PMID 19023099.


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