TRAPPC9

Protein-coding gene in the species Homo sapiens

TRAPPC9

Identifiers

Aliases

TRAPPC9, IBP, IKBKBBP, MRT13, NIBP, TRS120, T1, trafficking protein particle complex 9, trafficking protein particle complex subunit 9

External IDs

OMIM: 611966; MGI: 1923760; HomoloGene: 81931; GeneCards: TRAPPC9; OMA:TRAPPC9 - orthologs

Gene location (Human)

Chr.	Chromosome 8 (human)^[1]

Band	8q24.3	Start	139,727,725 bp^[1]
Band	8q24.3	End	140,458,579 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 15 (mouse)^[2]

Band	15\|15 D3	Start	72,461,469 bp^[2]
Band	15\|15 D3	End	72,933,053 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

muscle of thigh

gastrocnemius muscle

apex of heart

pancreatic ductal cell

ganglionic eminence

right uterine tube

prefrontal cortex

anterior pituitary

islet of Langerhans

tendon of biceps brachii

Top expressed in

neural layer of retina

muscle of thigh

dentate gyrus of hippocampal formation granule cell

primary visual cortex

right kidney

spermatocyte

cerebellar cortex

habenula

central gray substance of midbrain

seminiferous tubule

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	protein binding
Cellular component	cytoplasm cytosol trans-Golgi network Golgi apparatus endoplasmic reticulum Golgi membrane TRAPP complex
Biological process	cell differentiation COPII vesicle coating positive regulation of NF-kappaB transcription factor activity neuron differentiation cerebral cortex development
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


83696


76510

Ensembl


ENSG00000167632


ENSMUSG00000047921

UniProt


Q96Q05


Q3U0M1

RefSeq (mRNA)

NM_001160372 NM_031466 NM_001321646 NM_001374682 NM_001374683
NM_001374684


NM_001164641 NM_001164642 NM_001164643 NM_029640 NM_180662

RefSeq (protein)

NP_001153844 NP_001308575 NP_113654 NP_001361611 NP_001361612
NP_001361613


NP_001158113 NP_001158115 NP_083916 NP_850993

Location (UCSC)

Chr 8: 139.73 – 140.46 Mb

Chr 15: 72.46 – 72.93 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Trafficking protein particle complex 9 is a protein that in humans is encoded by the TRAPPC9 gene.^[5]

Function

This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive mental retardation. Alternatively spliced transcript variants have been described.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167632 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000047921 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Trafficking protein particle complex 9". Retrieved 2017-06-10.

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Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
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Zong M, Wu XG, Chan CW, Choi MY, Chan HC, Tanner JA, Yu S (2011). "The adaptor function of TRAPPC2 in mammalian TRAPPs explains TRAPPC2-associated SEDT and TRAPPC9-associated congenital intellectual disability". PLOS ONE. 6 (8): e23350. Bibcode:2011PLoSO...623350Z. doi:10.1371/journal.pone.0023350. PMC 3156116. PMID 21858081.