UNC5CL

Protein-coding gene in the species Homo sapiens
UNC5CL
Identifiers
AliasesUNC5CL, MUXA, ZUD, unc-5 family C-terminal like
External IDsOMIM: 617464; MGI: 1923839; HomoloGene: 18319; GeneCards: UNC5CL; OMA:UNC5CL - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for UNC5CL
Genomic location for UNC5CL
Band6p21.1Start41,026,895 bp[1]
End41,039,221 bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for UNC5CL
Genomic location for UNC5CL
Band17|17 CStart48,761,929 bp[2]
End48,846,742 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • pancreatic epithelial cell

  • pancreatic ductal cell

  • mucosa of ileum

  • duodenum

  • right lobe of liver

  • body of pancreas

  • jejunal mucosa

  • human kidney

  • pylorus

  • body of stomach
Top expressed in
  • basilar part of occipital bone

  • jejunum

  • duodenum

  • humerus

  • splanchnocranium

  • hyoid bone

  • sphenoid bone

  • ileum

  • Meckel's cartilage

  • femur
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • peptidase activity
  • netrin receptor activity
Cellular component
  • cytoplasm
  • integral component of membrane
  • membrane
Biological process
  • positive regulation of I-kappaB kinase/NF-kappaB signaling
  • positive regulation of JNK cascade
  • signal transduction
  • proteolysis
  • netrin-activated signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

222643

76589

Ensembl

ENSG00000124602

ENSMUSG00000043592

UniProt

Q8IV45

Q6R653

RefSeq (mRNA)

NM_173561

NM_152823

RefSeq (protein)

NP_775832

n/a

Location (UCSC)Chr 6: 41.03 – 41.04 MbChr 17: 48.76 – 48.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Unc-5 homolog C (C. elegans)-like is a protein in humans that is encoded by the UNC5CL gene. [5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000124602 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043592 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Unc-5 homolog C (C. elegans)-like". Retrieved 2013-07-08.

Further reading


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