USP19 |
---|
|
Available structures |
---|
PDB | Ortholog search: PDBe RCSB |
---|
List of PDB id codes |
---|
1WH0, 4X3G |
|
|
Identifiers |
---|
Aliases | USP19, ZMYND9, ubiquitin specific peptidase 19 |
---|
External IDs | OMIM: 614471; MGI: 1918722; HomoloGene: 41730; GeneCards: USP19; OMA:USP19 - orthologs |
---|
Gene location (Human) |
---|
![Chromosome 3 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 (human)[1] |
---|
| Band | 3p21.31 | Start | 49,108,046 bp[1] |
---|
End | 49,120,938 bp[1] |
---|
|
Gene location (Mouse) |
---|
![Chromosome 9 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Ideogram_house_mouse_chromosome_9.svg/260px-Ideogram_house_mouse_chromosome_9.svg.png) | Chr. | Chromosome 9 (mouse)[2] |
---|
| Band | 9|9 F2 | Start | 108,367,801 bp[2] |
---|
End | 108,379,536 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - gastrocnemius muscle
- muscle of thigh
- right uterine tube
- right lobe of thyroid gland
- right adrenal cortex
- granulocyte
- apex of heart
- body of tongue
- right hemisphere of cerebellum
- left adrenal gland
|
| Top expressed in | - secondary oocyte
- primary oocyte
- zygote
- neural layer of retina
- muscle of thigh
- choroid plexus of fourth ventricle
- superior frontal gyrus
- granulocyte
- lip
- ventricular zone
|
| More reference expression data |
|
---|
BioGPS | |
---|
|
Gene ontology |
---|
Molecular function | - Hsp90 protein binding
- cysteine-type peptidase activity
- metal ion binding
- Lys48-specific deubiquitinase activity
- peptidase activity
- protein binding
- thiol-dependent deubiquitinase
- hydrolase activity
- ubiquitin protein ligase binding
| Cellular component | - integral component of membrane
- endoplasmic reticulum membrane
- membrane
- endoplasmic reticulum
- cytosol
- nucleus
| Biological process | - protein K48-linked deubiquitination
- regulation of protein stability
- ubiquitin-dependent protein catabolic process
- protein stabilization
- response to endoplasmic reticulum stress
- proteolysis
- regulation of ERAD pathway
- regulation of cellular response to hypoxia
- negative regulation of skeletal muscle tissue development
- positive regulation of cell cycle process
- ubiquitin-dependent ERAD pathway
- negative regulation of proteasomal protein catabolic process
- protein deubiquitination
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | NM_001199160 NM_001199161 NM_001199162 NM_006677 NM_001351098
|
---|
NM_001351099 NM_001351100 NM_001351101 NM_001351102 NM_001351103 NM_001351104 NM_001351105 NM_001351106 NM_001351107 NM_001351108 NM_001389594 NM_001389595 NM_001389596 NM_001389597 NM_001389598 NM_001389599 NM_001389600 NM_001389601 NM_001389602 NM_001389603 NM_001389604 NM_001389605 NM_001389606 NM_001389607 NM_001389608 NM_001400288 NM_001400290 NM_001400292 NM_001400293 NM_001400294 NM_001400295 NM_001400296 NM_001400297 NM_001400298 NM_001400299 |
| |
---|
NM_001168371 NM_001168372 NM_001168373 NM_027804 NM_145407 |
|
---|
RefSeq (protein) | NP_001186089 NP_001186090 NP_001186091 NP_006668 NP_001338027
|
---|
NP_001338028 NP_001338029 NP_001338030 NP_001338031 NP_001338032 NP_001338033 NP_001338034 NP_001338035 NP_001338036 NP_001338037 |
| |
---|
NP_001161843 NP_001161844 NP_001161845 NP_082080 NP_663382 |
|
---|
Location (UCSC) | Chr 3: 49.11 – 49.12 Mb | Chr 9: 108.37 – 108.38 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|