USP19

Protein-coding gene in the species Homo sapiens

USP19

Available structures

PDB

Ortholog search: PDBe RCSB

List of PDB id codes
1WH0, 4X3G

Identifiers

Aliases

USP19, ZMYND9, ubiquitin specific peptidase 19

External IDs

OMIM: 614471; MGI: 1918722; HomoloGene: 41730; GeneCards: USP19; OMA:USP19 - orthologs

Gene location (Human)

Chr.	Chromosome 3 (human)^[1]

Band	3p21.31	Start	49,108,046 bp^[1]
Band	3p21.31	End	49,120,938 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 9 (mouse)^[2]

Band	9\|9 F2	Start	108,367,801 bp^[2]
Band	9\|9 F2	End	108,379,536 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

gastrocnemius muscle

muscle of thigh

right uterine tube

right lobe of thyroid gland

right adrenal cortex

granulocyte

apex of heart

body of tongue

right hemisphere of cerebellum

left adrenal gland

Top expressed in

secondary oocyte

primary oocyte

zygote

neural layer of retina

muscle of thigh

choroid plexus of fourth ventricle

superior frontal gyrus

granulocyte

ventricular zone

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	Hsp90 protein binding cysteine-type peptidase activity metal ion binding Lys48-specific deubiquitinase activity peptidase activity protein binding thiol-dependent deubiquitinase hydrolase activity ubiquitin protein ligase binding
Cellular component	integral component of membrane endoplasmic reticulum membrane membrane endoplasmic reticulum cytosol nucleus
Biological process	protein K48-linked deubiquitination regulation of protein stability ubiquitin-dependent protein catabolic process protein stabilization response to endoplasmic reticulum stress proteolysis regulation of ERAD pathway regulation of cellular response to hypoxia negative regulation of skeletal muscle tissue development positive regulation of cell cycle process ubiquitin-dependent ERAD pathway negative regulation of proteasomal protein catabolic process protein deubiquitination
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


10869


71472

Ensembl


ENSG00000172046


ENSMUSG00000006676

UniProt


O94966


Q3UJD6

RefSeq (mRNA)

NM_001199160
NM_001199161
NM_001199162
NM_006677
NM_001351098

NM_001351099
NM_001351100
NM_001351101
NM_001351102
NM_001351103
NM_001351104
NM_001351105
NM_001351106
NM_001351107
NM_001351108
NM_001389594
NM_001389595
NM_001389596
NM_001389597
NM_001389598
NM_001389599
NM_001389600
NM_001389601
NM_001389602
NM_001389603
NM_001389604
NM_001389605
NM_001389606
NM_001389607
NM_001389608
NM_001400288
NM_001400290
NM_001400292
NM_001400293
NM_001400294
NM_001400295
NM_001400296
NM_001400297
NM_001400298
NM_001400299


NM_001168371 NM_001168372 NM_001168373 NM_027804 NM_145407

RefSeq (protein)

NP_001186089 NP_001186090 NP_001186091 NP_006668 NP_001338027
NP_001338028 NP_001338029 NP_001338030 NP_001338031 NP_001338032 NP_001338033 NP_001338034 NP_001338035 NP_001338036 NP_001338037


NP_001161843 NP_001161844 NP_001161845 NP_082080 NP_663382

Location (UCSC)

Chr 3: 49.11 – 49.12 Mb

Chr 9: 108.37 – 108.38 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Ubiquitin specific peptidase 19 is a protein that in humans is encoded by the USP19 gene. ^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000172046 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000006676 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Ubiquitin specific peptidase 19". Retrieved 2016-02-18.