WDR1 |
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Identifiers |
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Aliases | WDR1, AIP1, HEL-S-52, NORI-1, WD repeat domain 1, PFITS |
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External IDs | OMIM: 604734; MGI: 1337100; HomoloGene: 6628; GeneCards: WDR1; OMA:WDR1 - orthologs |
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Gene location (Human) |
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![Chromosome 4 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/04/Ideogram_human_chromosome_4.svg/300px-Ideogram_human_chromosome_4.svg.png) | Chr. | Chromosome 4 (human)[1] |
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| Band | 4p16.1 | Start | 10,074,339 bp[1] |
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End | 10,116,949 bp[1] |
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Gene location (Mouse) |
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![Chromosome 5 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ideogram_house_mouse_chromosome_5.svg/260px-Ideogram_house_mouse_chromosome_5.svg.png) | Chr. | Chromosome 5 (mouse)[2] |
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| Band | 5 B3|5 20.63 cM | Start | 38,684,156 bp[2] |
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End | 38,720,564 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - popliteal artery
- tibial arteries
- smooth muscle tissue
- right coronary artery
- body of uterus
- saphenous vein
- stromal cell of endometrium
- parotid gland
- thoracic aorta
- mucosa of sigmoid colon
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| Top expressed in | - ankle joint
- granulocyte
- mesenteric lymph nodes
- stroma of bone marrow
- transitional epithelium of urinary bladder
- corneal stroma
- mucous cell of stomach
- tibiofemoral joint
- left colon
- molar
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/2/28/PBB_GE_WDR1_200611_s_at_fs.png/250px-PBB_GE_WDR1_200611_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/PBB_GE_WDR1_200609_s_at_fs.png/250px-PBB_GE_WDR1_200609_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/c/cc/PBB_GE_WDR1_210935_s_at_fs.png/250px-PBB_GE_WDR1_210935_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - actin binding
- actin filament binding
| Cellular component | - extracellular region
- myelin sheath
- podosome
- cell junction
- cell projection
- extracellular exosome
- cytoskeleton
- actin filament
- cell-cell junction
- cytoplasm
- cytosol
- cortical actin cytoskeleton
- plasma membrane
| Biological process | - platelet degranulation
- hearing
- actin cytoskeleton organization
- regulation of ventricular cardiac muscle cell membrane repolarization
- regulation of oligodendrocyte differentiation
- maintenance of epithelial cell apical/basal polarity
- apical junction assembly
- regulation of actin filament depolymerization
- neutrophil mediated immunity
- regulation of cell shape
- actin filament fragmentation
- platelet formation
- positive regulation of actin filament depolymerization
- cortical cytoskeleton organization
- locomotion
- establishment of planar polarity of follicular epithelium
- sarcomere organization
- neutrophil migration
- actin filament depolymerization
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 4: 10.07 – 10.12 Mb | Chr 5: 38.68 – 38.72 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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