West Virginia Route 88

Major junctionsSouth end US 250 in LimestoneMajor intersections

• US 40 in Wheeling
• I-70 in Wheeling

North end WV 27 near Wellsburg LocationCountryUnited StatesStateWest VirginiaCountiesMarshall, Ohio, Brooke Highway system

• West Virginia State Highway System

• Interstate
• US
• State

← WV 87

→ WV 90

West Virginia Route 88 is a north–south state highway located within the northern panhandle of West Virginia. The southern terminus is at U.S. Route 250 in Limestone. The northern terminus is at West Virginia Route 27 five miles (8 km) east of Wellsburg and 400 yards (370 m) west of the Pennsylvania border.

WV 88 is cosigned with U.S. Route 40 (National Road) from Elm Grove to Woodsdale. It originally terminated in Marshall County, West Virginia. Portions of WV 88 in Ohio County were originally designated as WV 91 via 29th Street and terminated in South Wheeling. A few Ohio County roads are still under the old Route 91 designation. WV 88 from National Road in Woodsdale to the intersection with WV 67 is most commonly known as Bethany Pike and some road signs refer to WV 88 south from Bethlehem as "Fairmont Pike".

• Golden Palace, Limestone
• Oglebay Park, Wheeling
• West Liberty University, West Liberty
• Bethany College, Bethany

County	Location	mi	km	Destinations	Notes
Marshall	​	0.00	0.00	US 250 – Cameron, Moundsville
	​	4.02	6.47	WV 86 south – Glen Dale
Ohio	Wheeling			US 40 east (National Road) to I-70 / I-470 west	south end of US 40 overlap
				I-70 west – Columbus	I-70 exit 4
				US 40 west (National Road) to I-70	north end of US 40 overlap
Brooke	Bethany			WV 67 west – Wellsburg	south end of WV 67 overlap
				WV 67 east – Bethany	north end of WV 67 overlap
	​			WV 27
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus