YTHDC2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | YTHDC2, CAHL, YTH domain containing 2, hYTHDC2 |
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External IDs | OMIM: 616530; MGI: 2448561; HomoloGene: 11265; GeneCards: YTHDC2; OMA:YTHDC2 - orthologs |
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Gene location (Human) |
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![Chromosome 5 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/6/61/Ideogram_human_chromosome_5.svg/300px-Ideogram_human_chromosome_5.svg.png) | Chr. | Chromosome 5 (human)[1] |
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| Band | 5q22.2 | Start | 113,513,694 bp[1] |
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End | 113,595,285 bp[1] |
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Gene location (Mouse) |
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![Chromosome 18 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/5/5c/Ideogram_house_mouse_chromosome_18.svg/260px-Ideogram_house_mouse_chromosome_18.svg.png) | Chr. | Chromosome 18 (mouse)[2] |
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| Band | 18|18 B3 | Start | 44,960,813 bp[2] |
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End | 45,022,791 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - endothelial cell
- skin of thigh
- skin of hip
- hair follicle
- tibia
- Achilles tendon
- Epithelium of choroid plexus
- epithelium of nasopharynx
- Brodmann area 23
- germinal epithelium
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| Top expressed in | - secondary oocyte
- spermatocyte
- zygote
- cumulus cell
- pineal gland
- semi-lunar valve
- aortic valve
- lumbar spinal ganglion
- endothelial cell of lymphatic vessel
- tail of embryo
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - nucleotide binding
- protein binding
- RNA polymerase binding
- ATP binding
- hydrolase activity
- helicase activity
- nucleic acid binding
- ATP-dependent activity, acting on RNA
- RNA binding
- N6-methyladenosine-containing RNA binding
- 3'-5' RNA helicase activity
| Cellular component | - endoplasmic reticulum
- cytoplasm
- nucleus
- ribonucleoprotein granule
| Biological process | - response to tumor necrosis factor
- RNA processing
- response to interleukin-1
- positive regulation by host of viral genome replication
- spermatogenesis
- spermatid development
- cell differentiation
- oogenesis
- oocyte development
- meiosis
- germline cell cycle switching, mitotic to meiotic cell cycle
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_022828 NM_001345975 NM_001345976 |
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RefSeq (protein) | |
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NP_001332904 NP_001332905 NP_073739 |
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Location (UCSC) | Chr 5: 113.51 – 113.6 Mb | Chr 18: 44.96 – 45.02 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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