ZHX2 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e7/Protein_ZHX2_PDB_2dmp.png/250px-Protein_ZHX2_PDB_2dmp.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2DMP, 3NAU |
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Identifiers |
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Aliases | ZHX2, AFR1, RAF, zinc fingers and homeoboxes 2 |
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External IDs | OMIM: 609185; MGI: 2683087; HomoloGene: 8968; GeneCards: ZHX2; OMA:ZHX2 - orthologs |
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Gene location (Human) |
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![Chromosome 8 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/6/60/Ideogram_human_chromosome_8.svg/300px-Ideogram_human_chromosome_8.svg.png) | Chr. | Chromosome 8 (human)[1] |
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| Band | 8q24.13 | Start | 122,781,655 bp[1] |
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End | 122,974,510 bp[1] |
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Gene location (Mouse) |
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![Chromosome 15 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/1/13/Ideogram_house_mouse_chromosome_15.svg/260px-Ideogram_house_mouse_chromosome_15.svg.png) | Chr. | Chromosome 15 (mouse)[2] |
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| Band | 15 D1|15 24.01 cM | Start | 57,558,061 bp[2] |
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End | 57,703,228 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - superficial temporal artery
- dorsal motor nucleus of vagus nerve
- saphenous vein
- Skeletal muscle tissue of rectus abdominis
- inferior olivary nucleus
- internal globus pallidus
- Skeletal muscle tissue of biceps brachii
- right ventricle
- caput epididymis
- lactiferous duct
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| Top expressed in | - knee joint
- triceps brachii muscle
- vastus lateralis muscle
- otolith organ
- temporal muscle
- utricle
- skeletal muscle tissue
- medial head of gastrocnemius muscle
- granulocyte
- sternocleidomastoid muscle
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/d/d5/PBB_GE_ZHX2_203556_at_fs.png/250px-PBB_GE_ZHX2_203556_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - DNA-binding transcription factor activity
- DNA binding
- protein binding
- protein homodimerization activity
- transcription corepressor activity
- metal ion binding
- identical protein binding
- protein heterodimerization activity
- nucleic acid binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
| Cellular component | - nucleus
- nucleoplasm
- cytosol
- plasma membrane
| Biological process | - regulation of transcription by RNA polymerase II
- negative regulation of transcription, DNA-templated
- regulation of transcription, DNA-templated
- negative regulation of transcription by RNA polymerase II
- mRNA catabolic process
- negative regulation of neuron differentiation
- somatic stem cell population maintenance
- transcription, DNA-templated
- retinal bipolar neuron differentiation
- nervous system development
- cell differentiation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 8: 122.78 – 122.97 Mb | Chr 15: 57.56 – 57.7 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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