ZMIZ2

Protein-coding gene in the species Homo sapiens
ZMIZ2
Identifiers
AliasesZMIZ2, NET27, TRAFIP20, ZIMP7, hZIMP7, zinc finger MIZ-type containing 2
External IDsOMIM: 611196; MGI: 106374; HomoloGene: 18000; GeneCards: ZMIZ2; OMA:ZMIZ2 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for ZMIZ2
Genomic location for ZMIZ2
Band7p13Start44,748,581 bp[1]
End44,769,881 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for ZMIZ2
Genomic location for ZMIZ2
Band11 A1|11 3.95 cMStart6,389,074 bp[2]
End6,406,158 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • endothelial cell

  • right uterine tube

  • right lobe of thyroid gland

  • left lobe of thyroid gland

  • right frontal lobe

  • Region I of hippocampus proper

  • anterior pituitary

  • body of pancreas

  • right hemisphere of cerebellum

  • granulocyte
Top expressed in
  • perirhinal cortex

  • superior frontal gyrus

  • primary visual cortex

  • entorhinal cortex

  • dentate gyrus of hippocampal formation granule cell

  • CA3 field

  • Ileal epithelium

  • ventricular zone

  • cerebellar cortex

  • lip
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
  • zinc ion binding
  • protein binding
  • nuclear receptor coactivator activity
  • metal ion binding
Cellular component
  • nuclear replication fork
  • mitochondrion
  • nucleus
  • nucleoplasm
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • positive regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

83637

52915

Ensembl

ENSG00000122515

ENSMUSG00000041164

UniProt

Q8NF64

Q8CIE2

RefSeq (mRNA)

NM_001300959
NM_031449
NM_174929

NM_001005867
NM_028601

RefSeq (protein)

NP_001287888
NP_113637
NP_777589

NP_001005867
NP_082877

Location (UCSC)Chr 7: 44.75 – 44.77 MbChr 11: 6.39 – 6.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger MIZ domain-containing protein 2 is a protein that in humans is encoded by the ZMIZ2 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000122515 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041164 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: ZMIZ2 zinc finger, MIZ-type containing 2".

Further reading

  • Sanger Centre, The; Washington University Genome Sequencing Cente, The (Nov 1998). "Toward a complete human genome sequence". Genome Research. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
  • Ueki N, Oda T, Kondo M, Yano K, Noguchi T, Muramatsu M (Dec 1998). "Selection system for genes encoding nuclear-targeted proteins". Nature Biotechnology. 16 (13): 1338–42. doi:10.1038/4315. PMID 9853615. S2CID 20001769.
  • Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Nagase T, Kikuno R, Ohara O (Aug 2001). "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins". DNA Research. 8 (4): 179–87. doi:10.1093/dnares/8.4.179. PMID 11572484.
  • Huang CY, Beliakoff J, Li X, Lee J, Li X, Sharma M, Lim B, Sun Z (Dec 2005). "hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes". Molecular Endocrinology. 19 (12): 2915–29. doi:10.1210/me.2005-0097. PMID 16051670.
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.


  • v
  • t
  • e