ZSCAN21

Protein-coding gene in the species Homo sapiens
ZSCAN21
Identifiers
AliasesZSCAN21, NY-REN-21, ZNF38, Zipro1, zinc finger and SCAN domain containing 21
External IDsOMIM: 601261; MGI: 99182; HomoloGene: 56530; GeneCards: ZSCAN21; OMA:ZSCAN21 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for ZSCAN21
Genomic location for ZSCAN21
Band7q22.1Start100,049,774 bp[1]
End100,065,040 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for ZSCAN21
Genomic location for ZSCAN21
Band5 G2|5 76.96 cMStart138,115,165 bp[2]
End138,132,527 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • oocyte

  • secondary oocyte

  • gonad

  • parotid gland

  • ventricular zone

  • testicle

  • ganglionic eminence

  • endothelial cell

  • right uterine tube

  • gastrocnemius muscle
Top expressed in
  • otic vesicle

  • saccule

  • seminiferous tubule

  • Rostral migratory stream

  • medullary collecting duct

  • maxillary prominence

  • otic placode

  • fossa

  • ganglionic eminence

  • mandibular prominence
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • RNA polymerase II cis-regulatory region sequence-specific DNA binding
  • DNA binding
  • DNA-binding transcription activator activity, RNA polymerase II-specific
  • protein binding
  • metal ion binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • nucleus
Biological process
  • positive regulation of transcription, DNA-templated
  • regulation of transcription, DNA-templated
  • positive regulation of transcription by RNA polymerase II
  • transcription, DNA-templated
  • transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

7589

22697

Ensembl

ENSG00000166529

ENSMUSG00000037017

UniProt

Q9Y5A6

Q07231

RefSeq (mRNA)

NM_145914
NM_001362779
NM_001362780
NM_001362781

NM_001044703
NM_001044704
NM_001044705
NM_011757

RefSeq (protein)

NP_666019
NP_001349708
NP_001349709
NP_001349710

NP_001038168
NP_001038169
NP_001038170
NP_035887

Location (UCSC)Chr 7: 100.05 – 100.07 MbChr 5: 138.12 – 138.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger and SCAN domain-containing protein 21 is a protein that in humans is encoded by the ZSCAN21 gene.[5][6][7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000166529 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037017 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Thiesen HJ (Mar 1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–374. PMID 2288909.
  6. ^ Huebner K, Druck T, Croce CM, Thiesen HJ (May 1991). "Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering". Am J Hum Genet. 48 (4): 726–740. PMC 1682948. PMID 2014798.
  7. ^ "Entrez Gene: ZSCAN21 zinc finger and SCAN domain containing 21".

Further reading

  • Carneiro FR; Silva TC; Alves AC; et al. (2006). "Spectroscopic characterization of the tumor antigen NY-REN-21 and identification of heterodimer formation with SCAND1". Biochem. Biophys. Res. Commun. 343 (1): 260–268. doi:10.1016/j.bbrc.2006.02.140. PMID 16540086.
  • Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Scherer SW; Cheung J; MacDonald JR; et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–772. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
  • Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Wiemann S; Weil B; Wellenreuther R; et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–435. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
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