Fibronektina

Identifikadoreak
Taxoia	Homo sapiens
Kokapena
Hasiera	^[1]
Amaiera	^[2]
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Transkripzioak
Gene-adierazpen eredua

Ontologia
Funtzio-molekularrak	Ikusi heparin binding ^(en) collagen binding ^(en) integrin binding ^(en) proteina lotura identical protein binding ^(en) peptidase activator activity ^(en) protease binding ^(en)
Osagai-zelularra	Ikusi blood microparticle ^(en) Zelula kanpoko matrize Fibrinogeno zelulaz kanpoko eremu basement membrane ^(en) apical plasma membrane ^(en) extracellular exosome ^(en) platelet alpha granule lumen ^(en) endoplasmic reticulum-Golgi intermediate compartment ^(en) extracellular fluid ^(en) zelulaz kanpoko eremu
Prozesu-biologikoak	Ikusi regulation of protein phosphorylation ^(en) calcium-independent cell-matrix adhesion ^(en) endodermal cell differentiation ^(en) positive regulation of fibroblast proliferation ^(en) positive regulation of substrate-dependent cell migration, cell attachment to substrate ^(en) platelet degranulation ^(en) extracellular matrix disassembly ^(en) orbaintze positive regulation of peptidase activity ^(en) peptide cross-linking ^(en) Atxikipen zelular positive regulation of gene expression ^(en) acute-phase response ^(en) angiogenesis ^(en) positive regulation of cell population proliferation ^(en) regulation of cell shape ^(en) regulation of ERK1 and ERK2 cascade ^(en) cell-substrate junction assembly ^(en) substrate adhesion-dependent cell spreading ^(en) integrin activation ^(en) positive regulation of axon extension ^(en) cell-matrix adhesion ^(en) leukocyte migration ^(en) response to wounding ^(en) extracellular matrix organization ^(en)

Fibronektina^[3] ornodun guztietan dagoen glukoproteina bat da. Fibronektina 440 kDa inguruko glukoproteina bat da, forma monomeriko edo dimerikoan ager daitekeena, eta animalia-ehun zelular gehienen zelula kanpoko matrizean dago. 20 isoforma ezberdin ere badaude. Fibronektina plasmatikoa deritzona, disolbagarria da eta odolean zirkulatzen du, non odolaren koagulazioa, orbaintzea eta fagozitosia areagotzen dituen.