peptide insulinotrope dépendant du glucose |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/0/09/2OBU.png/250px-2OBU.png) |
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Structures disponibles |
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PDB | Recherche d'orthologue: PDBe RCSB |
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Identifiants PDB |
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2L71, 2B4N, 2OBU, 2QKH, 2L70, 1T5Q |
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Identifiants |
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Aliases | GIP |
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IDs externes | OMIM: 137240 MGI: 107504 HomoloGene: 3043 GeneCards: GIP |
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Position du gène (Homme) |
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![Chromosome 17 humain](//upload.wikimedia.org/wikipedia/commons/thumb/0/00/Ideogram_human_chromosome_17.svg/300px-Ideogram_human_chromosome_17.svg.png) | Chr. | Chromosome 17 humain[1] |
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| Locus | 17q21.32 | Début | 48,958,554 bp[1] |
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Fin | 48,968,596 bp[1] |
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Position du gène (Souris) |
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![Chromosome 11 (souris)](//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Ideogram_house_mouse_chromosome_11.svg/260px-Ideogram_house_mouse_chromosome_11.svg.png) | Chr. | Chromosome 11 (souris)[2] |
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| Locus | 11|11 D | Début | 95,915,371 bp[2] |
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Fin | 95,921,657 bp[2] |
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Expression génétique |
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Bgee | Humain | Souris (orthologue) |
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Fortement exprimé dans | - muqueuse jéjunale
- duodénum
- gonade
- testicule
- buccal mucosa cell
- pancreatic ductal cell
- stromal cell of endometrium
- nerf sural
- placenta
- foie
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| Fortement exprimé dans | - duodénum
- crypt of lieberkuhn of small intestine
- Jéjunum
- Épithélium intestinal
- epithelium of small intestine
- villosité intestinale
- embryon
- épithélium pigmentaire rétinien
- morula
- corneal stroma
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| Plus de données d'expression de référence |
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BioGPS | |
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Gene Ontology |
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Fonction moléculaire | - hormone activity
- liaison protéique
- signaling receptor binding
| Composant cellulaire | - cytoplasme
- endoplasmic reticulum lumen
- région extracellulaire
- neuronal cell body
- secretory granule lumen
- milieu extracellulaire
| Processus biologique | - response to selenium ion
- response to amino acid
- response to organic cyclic compound
- digestive system development
- regulation of insulin secretion
- adult locomotory behavior
- gestation
- response to peptide hormone
- positive regulation of cAMP-mediated signaling
- mémoire
- response to glucose
- response to lipid
- response to nutrient levels
- positive regulation of synaptic transmission
- Comportement exploratoire
- response to axon injury
- response to starvation
- nociception
- positive regulation of glucagon secretion
- positive regulation of glucose transmembrane transport
- response to carbohydrate
- triglyceride homeostasis
- transduction de signal
- response to acidic pH
- endocrine pancreas development
- positive regulation of insulin secretion
- potentialisation à long terme
- regulation of signaling receptor activity
- G protein-coupled receptor signaling pathway
- regulation of fatty acid biosynthetic process
| Sources:Amigo / QuickGO |
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Orthologues |
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Espèces | Homme | Souris |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protéine) | | |
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Localisation (UCSC) | Chr 17: 48.96 – 48.97 Mb | Chr 11: 95.92 – 95.92 Mb |
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Publication PubMed | [3] | [4] |
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Wikidata |
Voir/Editer Humain | Voir/Editer Souris |
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