CTNNAL1 |
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Pengidentifikasi |
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Alias | CTNNAL1, ACRP, CLLP, alpha-CATU, catenin alpha like 1 |
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ID eksternal | OMIM: 604785 MGI: 1859649 HomoloGene: 2815 GeneCards: CTNNAL1 |
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Pola ekspresi RNA |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/4/40/PBB_GE_CTNNAL1_202468_s_at_fs.png/250px-PBB_GE_CTNNAL1_202468_s_at_fs.png) | Referensi data ekspresi selengkapnya |
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Ontologi gen |
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Fungsi molekuler | • actin filament binding • GO:0001948, GO:0016582 Ikatan protein plasma • cadherin binding
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Komponen seluler | • sitoplasma • sitosol • Membran sel • Sitoskeleton • membran
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Proses biologis | • Adhesi sel • Rho protein signal transduction
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Sumber:Amigo / QuickGO |
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Ortolog |
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Spesies | Manusia | Tikus |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Lokasi (UCSC) | n/a | n/a |
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Pencarian PubMed | [1] | [2] |
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Wikidata |
Lihat/Sunting Manusia | Lihat/Sunting Tikus |
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Alpha-catulin adalah protein yang pada manusia dikodekan oleh gen CTNNAL1.[3][4]
Interaksi
CTNNAL1 telah terbukti berinteraksi dengan AKAP13.[5]
Referensi
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Zhang JS, Nelson M, Wang L, Liu W, Qian CP, Shridhar V, Urrutia R, Smith DI (Jan 1999). "Identification and chromosomal localization of CTNNAL1, a novel protein homologous to alpha-catenin". Genomics. 54 (1): 149–54. doi:10.1006/geno.1998.5458. PMID 9806841.
- ^ "Entrez Gene: CTNNAL1 catenin (cadherin-associated protein), alpha-like 1".
- ^ Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D (Nov 2002). "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation". J. Biol. Chem. 277 (47): 45361–70. doi:10.1074/jbc.M202447200
. PMID 12270917.
Pranala luar
- Lokasi genom CTNNAL1 manusia dan halaman rincian gen CTNNAL1 dalam UCSC Genome Browser.
Bacaan lanjutan
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Janssens B, Staes K, van Roy F (1999). "Human alpha-catulin, a novel alpha-catenin-like molecule with conserved genomic structure, but deviating alternative splicing". Biochim. Biophys. Acta. 1447 (2–3): 341–7. doi:10.1016/s0167-4781(99)00170-0. PMID 10542337.
- Demacio PC, Ray PN (2002). "Alpha-catulin maps to the familial dysautonomia region on 9q31". Genome. 44 (6): 990–4. doi:10.1139/gen-44-6-990. PMID 11768226.
- Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D (2003). "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation". J. Biol. Chem. 277 (47): 45361–70. doi:10.1074/jbc.M202447200
. PMID 12270917. - Shieh YS, Chang LC, Chiu KC, Wu CW, Lee HS (2003). "Cadherin and catenin expression in mucoepidermoid carcinoma: correlation with histopathologic grade, clinical stage, and patient outcome". J. Oral Pathol. Med. 32 (5): 297–304. doi:10.1034/j.1600-0714.2003.00144.x. PMID 12694354.
- Surpili MJ, Delben TM, Kobarg J (2004). "Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1". Biochemistry. 42 (51): 15369–76. doi:10.1021/bi034575v. PMID 14690447.
- Merdek KD, Nguyen NT, Toksoz D (2004). "Distinct Activities of the α-Catenin Family, α-Catulin and α-Catenin, on β-Catenin-Mediated Signaling". Mol. Cell. Biol. 24 (6): 2410–22. doi:10.1128/mcb.24.6.2410-2422.2004. PMC 355851
. PMID 14993280.