Aducina gama

ADD3
Identificadores
Nomes alternativosADD3
IDs externosOMIM: 601568 HomoloGene: 40893 GeneCards: ADD3
Ontologia genética
Função molecular structural molecule activity
actin binding
structural constituent of cytoskeleton
calmodulin binding
spectrin binding
actin filament binding
Componente celular condensed nuclear chromosome
citosol
membrana plasmática
cell cortex
citoesqueleto
membrane
brush border
cariolinfa
cell-cell junction
citoplasma
GO:0097483, GO:0097481 postsynaptic density
plasma membrane raft
Processo biológico transmembrane transport
cytoskeleton organization
barbed-end actin filament capping
actin filament bundle assembly
Sources:Amigo / QuickGO
Padrão de expressão RNA




Mais dados de referência de expressão
Ortólogos
EspécieHumanoRato
Entrez

120

n/a

Ensembl

ENSG00000148700

n/a

UniProt

Q9UEY8

n/a

RefSeq (mRNA)
NM_001121
NM_016824
NM_019903
NM_001320591
NM_001320592

NM_001320593
NM_001320594

n/a

RefSeq (proteína)
NP_001112
NP_001307520
NP_001307521
NP_001307522
NP_001307523

NP_058432
NP_063968

n/a

Localização (UCSC)n/an/a
Pesquisa PubMed[1]n/a
Wikidata
Ver/Editar Humano

Aducina gama é uma proteína que em humanos é codificada pelo gene ADD3.[2][3]

Referências

  1. «Human PubMed Reference:» 
  2. Katagiri T, Ozaki K, Fujiwara T, Shimizu F, Kawai A, Okuno S, Suzuki M, Nakamura Y, Takahashi E, Hirai Y (dezembro de 1996). «Cloning, expression and chromosome mapping of adducin-like 70 (ADDL), a human cDNA highly homologous to human erythrocyte adducin». Cytogenet Cell Genet. 74 (1–2): 90–5. PMID 8893809. doi:10.1159/000134389 
  3. «Entrez Gene: ADD3 adducin 3 (gamma)» 
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Leitura adicional

  • Kaiser HW, O'Keefe E, Bennett V (1989). «Adducin: Ca++-dependent association with sites of cell-cell contact». J. Cell Biol. 109 (2): 557–69. PMC 2115715Acessível livremente. PMID 2503523. doi:10.1083/jcb.109.2.557 
  • Maruyama K, Sugano S (1994). «Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides». Gene. 138 (1–2): 171–4. PMID 8125298. doi:10.1016/0378-1119(94)90802-8 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). «Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library». Gene. 200 (1–2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3 
  • Gilligan DM, Lozovatsky L, Gwynn B, et al. (1999). «Targeted disruption of the β adducin gene (Add2) causes red blood cell spherocytosis in mice». Proc. Natl. Acad. Sci. U.S.A. 96 (19): 10717–22. PMC 17949Acessível livremente. PMID 10485892. doi:10.1073/pnas.96.19.10717 
  • Citterio L, Azzani T, Duga S, Bianchi G (2000). «Genomic organization of the human gamma adducin gene». Biochem. Biophys. Res. Commun. 266 (1): 110–4. PMID 10581174. doi:10.1006/bbrc.1999.1769 
  • Gilligan DM, Sarid R, Weese J (2002). «Adducin in platelets: activation-induced phosphorylation by PKC and proteolysis by calpain». Blood. 99 (7): 2418–26. PMID 11895774. doi:10.1182/blood.V99.7.2418 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). «Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences». Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241Acessível livremente. PMID 12477932. doi:10.1073/pnas.242603899 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). «The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)». Genome Res. 14 (10B): 2121–7. PMC 528928Acessível livremente. PMID 15489334. doi:10.1101/gr.2596504 
  • Gocke CB, Yu H, Kang J (2005). «Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates». J. Biol. Chem. 280 (6): 5004–12. PMID 15561718. doi:10.1074/jbc.M411718200 
  • Lanzani C, Citterio L, Jankaricova M, et al. (2005). «Role of the adducin family genes in human essential hypertension». J. Hypertens. 23 (3): 543–9. PMID 15716695. doi:10.1097/01.hjh.0000160210.48479.78 
  • Yenerel MN, Sundell IB, Weese J, et al. (2005). «Expression of adducin genes during erythropoiesis: a novel erythroid promoter for ADD2». Exp. Hematol. 33 (7): 758–66. PMID 15963851. doi:10.1016/j.exphem.2005.03.015 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). «Global, in vivo, and site-specific phosphorylation dynamics in signaling networks». Cell. 127 (3): 635–48. PMID 17081983. doi:10.1016/j.cell.2006.09.026 
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