Adenilosukcinatna lijaza
Adenilosukcinatna lijaza | |||||||||
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Tetramer adenilosukcinatne lijaze (čovjek) | |||||||||
Identifikatori | |||||||||
EC broj | 4.3.2.2 | ||||||||
CAS broj | 9027-81-0 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Adenilosukcinatna lijaza (EC 4.3.2.2, adenilosukcinaza, sukcino AMP-lijaza, 6-N-(1,2-dikarboksietil)AMP AMP-lijaza, 6-N-(1,2-dikarboksietil)AMP AMP-lijaza (formira fumarat)) je enzim sa sistematskim imenom N6-(1,2-dikarboksietil)AMP AMP-lijaza (formira fumarat).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (1) N6-(1,2-dikarboksietil)AMP fumarat + AMP
- (2) (S)-2-[5-amino-1-(5-fosfo-D-ribozil)imidazol-4-karboxamido]sukcinat fumarat + 5-amino-1-(5-fosfo-D-ribozil)imidazol-4-karboksamid
Ovaj enzim takođe deluje na 1-(5-fosforibozil)-4-(N-sukcinokarboksamid)-5-aminoimidazol.
Reference
- ↑ Carter, C.E. and Cohen, L.H. (1956). „The preparation and properties of adenylosuccinase and adenylosuccinic acid”. J. Biol. Chem. 222: 17-30. PMID 13366975.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Vanjske veze
- MeSH Adenylosuccinate+lyase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6