Cistationinska b-lijaza

Cistationinska b-lijaza
Cistationinska b-lijaza tetramer, E.Coli
Identifikatori
EC broj 4.4.1.8
CAS broj 2613435
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC articles
PubMed articles
NCBI Protein search

Cistationinska b-lijaza (EC 4.4.1.8, beta-cistationaza, cistinska lijaza, cistationinska L-homocistein-lijaza (deaminacija), L-cistationinska L-homocistein-lijaza (deaminacija)) je enzim sa sistematskim imenom L-cistationin L-homocistein-lijaza (deaminacija, formira piruvat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

L-cistationin + H2O {\displaystyle \rightleftharpoons } L-homocistein + NH3 + piruvat

Ovaj enzim je piridoksal-fosfatni protein.

Reference

  1. Anderson, N.W. and Thompson, J.F. (1979). „Cystine lyase: β-cystathionase from turnip roots”. Phytochemistry 18: 1953-1958. 
  2. Flavin, M. and Slaughter, C. (1964). „Cystathionine cleavage enzymes of Neurospora”. J. Biol. Chem. 239: 2212-2219. PMID 14209950. 

Literatura

  • Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
  • Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
  • Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Spoljašnje veze

  • MeSH Cystathionine+beta-lyase
  • p
  • r
  • u
TemeTipovi
EC1 Oksidoreduktaze/spisak  • EC2 Transferaze/spisak  • EC3 Hidrolaze/spisak  • EC4 Lijaze/spisak  • EC5 Izomeraze/spisak  • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6