Tiouracil
Tiouracil | |||
---|---|---|---|
![]() | |||
IUPAC ime |
| ||
Identifikacija | |||
CAS registarski broj | 141-90-2 ![]() | ||
PubChem[1][2] | 1269845 | ||
ChemSpider[3] | 1066108 ![]() | ||
UNII | 59X161SCYL ![]() | ||
KEGG[4] | C19304 | ||
MeSH | Thiouracil | ||
ChEBI | 348530 | ||
ChEMBL[5] | CHEMBL345768 ![]() | ||
Jmol-3D slike | Slika 1 | ||
| |||
| |||
Svojstva | |||
Molekulska formula | C4H4N2OS | ||
Molarna masa | 128,153 | ||
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala | |||
Infobox references |
Tiouracil je sumporni analog uracila, kao i familija molekula baziranih na toj strukturi. Ova supstanca je istorijski značajna u pripremi antitiroida. Tiouracil je prvi put korišten 1943. kao terapija za Gravesovu bolest.[6] Lek je ostao u oputrebi.
Reference
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
- ↑ Gerabek W.: Enzyklopädie Medizingeschichte, S 152, 2005
Spoljašnje veze
![]() | Portal Hemija |