AMP—timidin kinaza
AMP—timidin kinaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.1.114 | ||||||||
CAS broj | 60440-28-0 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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AMP—timidin kinaza (EC 2.7.1.114, adenilat-nukleozidna fosfotransferaza) je enzim sa sistematskim imenom AMP:timidin 5'-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- AMP + timidin adenozin + dTMP
Dezoksipirimidinski kinazni kompleks indukovan virusom Herpes simplex katalizuje ovu reakciju, kao i reacije enzima EC 2.7.1.21 (timidin kinaza), EC 2.7.1.118 (ADP---timidin kinaza) i EC 2.7.4.9 (dTMP kinaza).
Reference
- ^ Falke, D., Labenz, J., Brauer, D. and Muller, W.E.G. (1982). „Adenosine diphosphate: thymidine 5′-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase”. Biochim. Biophys. Acta. 708: 99—103. PMID 6293576. CS1 одржавање: Вишеструка имена: списак аутора (веза)
- ^ Falke, D., Nehrbass, W., Brauer, D. and Mueller, W.E.G. (1981). „Adenylic acid: deoxythymidine 5′-phosphotransferase: evidence for the existence of a novel Herpes simplex virus-induced enzyme”. J. Gen. Virol. 53: 247—255. PMID 6267178. CS1 одржавање: Вишеструка имена: списак аутора (веза)
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
- AMP---thymidine+kinase на US National Library of Medicine Medical Subject Headings (MeSH)
- п
- р
- у
- EC1 Oksidoreduktaze /spisak
- EC2 Transferaze /spisak
- EC3 Hidrolaze /spisak
- EC4 Lijaze /spisak
- EC5 Izomeraze /spisak
- EC6 Ligaze /spisak
- B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6