ACER3 : Kaynakça, Ek okuma Vikipedi: Özgür Ansiklopedi

ACER3

Tanımlayıcılar

Başka adlar

ACER3

Dış kimlikler

OMIM: 617036 MGI: 1913440 HomoloGene: 5410 GeneCards: ACER3

Gen ontolojisi
Moleküler işlevi	• hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides • hydrolase activity • phytoceramidase activity • N-acylsphingosine amidohydrolase activity • dihydroceramidase activity • ceramidase activity • calcium ion binding • zinc ion binding • metal ion binding
Hücresel bileşeni	• integral component of membrane • integral component of Golgi membrane • integral component of endoplasmic reticulum membrane • Golgi membrane • Golgi aygıtı • endoplasmic reticulum membrane • Endoplazmik retikulum • membrane
Biyolojik süreci	• sphingosine biosynthetic process • sphingolipid biosynthetic process • phytosphingosine biosynthetic process • ceramide metabolic process • positive regulation of cell population proliferation • inflammatory response • myelination • regulation of programmed cell death • ceramide catabolic process • lipid metabolism • sphingolipid metabolic process
Kaynaklar:Amigo / QuickGO

Ortologlar

Türler

İnsan

Fare

Entrez


55331


66190

Ensembl


ENSG00000078124


ENSMUSG00000030760

UniProt


Q9NUN7


Q9D099

RefSeq (mRNA)


NM_001300953 NM_001300954 NM_001300955 NM_018367


NM_025408

RefSeq (protein)


NP_001287882 NP_001287883 NP_001287884 NP_060837


NP_079684 NP_001347544 NP_001347545 NP_001347546

Yerleşim (UCSC)

Krom. 11: 76.86 – 77.03 Mb

n/a

PubMed araması

^[2]

^[3]

Vikiveri

İnsan'ı Gör/Düzenle

Fare'yi Gör/Düzenle

Alkalin seramidaz 3, insanların 11. kromozomunda yer alan ACER3 geni tarafından kodlanan bir seramidaz enzimidir.^[4]^[5]

Kaynakça

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000078124 - Ensembl, May 2017
^ "İnsan PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine. Arşivlenmesi gereken bağlantıya sahip kaynak şablonu içeren maddeler (link)
^ "Fare PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine. Arşivlenmesi gereken bağlantıya sahip kaynak şablonu içeren maddeler (link)
^ Mao C, Xu R, Szulc ZM, Bielawska A, Galadari SH, Obeid LM (July 2001). "Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide". J. Biol. Chem. 276 (28). ss. 26577-88. doi:10.1074/jbc.M102818200. PMID 11356846.
^ Mao C, Obeid LM (September 2008). "Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate". Biochim. Biophys. Acta. 1781 (9). ss. 424-34. doi:10.1016/j.bbalip.2008.06.002. PMC 2614331 $2. PMID 18619555.

Strausberg RL, Feingold EA, Grouse LH, ve diğerleri. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26). ss. 16899-903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241 $2. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, ve diğerleri. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B). ss. 2121-7. doi:10.1101/gr.2596504. PMC 528928 $2. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, ve diğerleri. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1). ss. 40-5. doi:10.1038/ng1285. PMID 14702039.
Wheeler HE, Metter EJ, Tanaka T, ve diğerleri. (2009). Gibson G (Ed.). "Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging". PLOS Genet. 5 (10). ss. e1000685. doi:10.1371/journal.pgen.1000685. PMC 2752811 $2. PMID 19834535.