YTHDF3
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識別號 | |||||||||||||||||||||||||
别名 | YTHDF3;, YTH N6-methyladenosine RNA binding protein 3, DF3 | ||||||||||||||||||||||||
外部ID | MGI:1918850 HomoloGene:34991 GeneCards:YTHDF3 | ||||||||||||||||||||||||
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RNA表达模式 | |||||||||||||||||||||||||
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物種 | 人類 | 小鼠 | |||||||||||||||||||||||
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mRNA序列 |
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蛋白序列 |
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基因位置(UCSC) | Chr 8: 63.17 – 63.21 Mb | Chr 3: 16.24 – 16.27 Mb | |||||||||||||||||||||||
PubMed查找 | [3] | [4] | |||||||||||||||||||||||
維基數據 | |||||||||||||||||||||||||
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YTHDF3是一个位于人类第8号染色体上的基因,编码蛋白YTHDF3蛋白(YTHDF意为“YTH结构域家族”(英語:YTH domain family))。YTHDF3基因与YTHDF1属旁系同源,编码的YTHDF3蛋白功能可能是识别并结合N6-甲基腺苷(m6A)修饰的mRNA,并增加与之结合的mRNA易位效率[5][6][7]。
参见
- YTH结构域(英语:YTH protein domain)
- N6-甲基腺苷(m6A)
参考资料
- ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000185728 - Ensembl, May 2017
- ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000047213 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ YTHDF3 Gene. GeneCards. [2021-05-03]. (原始内容存档于2021-05-06).
- ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. Dec 2002, 99 (26): 16899–903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899.
- ^ Entrez Gene: YTHDF3 YTH domain family, member 3. [2021-05-03]. (原始内容存档于2010-12-05).
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