RAB11FIP2
Protein-coding gene in the species Homo sapiens
RAB11FIP2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | RAB11FIP2, Rab11-FIP2, nRip11, RAB11 family interacting protein 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 608599; MGI: 1922248; HomoloGene: 8937; GeneCards: RAB11FIP2; OMA:RAB11FIP2 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Rab11 family-interacting protein 2 is a protein that in humans is encoded by the RAB11FIP2 gene.[5][6][7]
Interactions
RAB11FIP2 has been shown to interact with MYO5B,[8] RAB11A[5][9][10] and RAB25.[9][10]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000107560 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040022 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b Lindsay AJ, McCaffrey MW (July 2002). "Rab11-FIP2 functions in transferrin recycling and associates with endosomal membranes via its COOH-terminal domain". J Biol Chem. 277 (30): 27193–9. doi:10.1074/jbc.M200757200. PMID 11994279.
- ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (July 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
- ^ "Entrez Gene: RAB11FIP2 RAB11 family interacting protein 2 (class I)".
- ^ Hales CM, Vaerman Jean-Pierre, Goldenring James R (Dec 2002). "Rab11 family interacting protein 2 associates with Myosin Vb and regulates plasma membrane recycling". J. Biol. Chem. 277 (52): 50415–21. doi:10.1074/jbc.M209270200. ISSN 0021-9258. PMID 12393859.
- ^ a b Hales CM, Griner R, Hobdy-Henderson K C, Dorn M C, Hardy D, Kumar R, Navarre J, Chan E K, Lapierre L A, Goldenring J R (October 2001). "Identification and characterization of a family of Rab11-interacting proteins". J. Biol. Chem. 276 (42): 39067–75. doi:10.1074/jbc.M104831200. ISSN 0021-9258. PMID 11495908.
- ^ a b Prekeris R, Davies J M, Scheller R H (October 2001). "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins". J. Biol. Chem. 276 (42): 38966–70. doi:10.1074/jbc.M106133200. ISSN 0021-9258. PMID 11481332.
Further reading
- Prekeris R, Davies JM, Scheller RH (2001). "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins". J. Biol. Chem. 276 (42): 38966–70. doi:10.1074/jbc.M106133200. PMID 11481332.
- Hales CM, Griner R, Hobdy-Henderson KC, Dorn MC, Hardy D, Kumar R, Navarre J, Chan EK, Lapierre LA (2001). "Identification and characterization of a family of Rab11-interacting proteins". J. Biol. Chem. 276 (42): 39067–75. doi:10.1074/jbc.M104831200. PMID 11495908.
- Wallace DM, Lindsay AJ, Hendrick AG, McCaffrey MW (2002). "The novel Rab11-FIP/Rip/RCP family of proteins displays extensive homo- and hetero-interacting abilities". Biochem. Biophys. Res. Commun. 292 (4): 909–15. doi:10.1006/bbrc.2002.6736. PMID 11944901.
- Cullis DN, Philip B, Baleja JD, Feig LA (2003). "Rab11-FIP2, an adaptor protein connecting cellular components involved in internalization and recycling of epidermal growth factor receptors". J. Biol. Chem. 277 (51): 49158–66. doi:10.1074/jbc.M206316200. PMID 12364336.
- Hales CM, Vaerman JP, Goldenring JR (2003). "Rab11 family interacting protein 2 associates with Myosin Vb and regulates plasma membrane recycling". J. Biol. Chem. 277 (52): 50415–21. doi:10.1074/jbc.M209270200. PMID 12393859.
- Wallace DM, Lindsay AJ, Hendrick AG, McCaffrey MW (2003). "Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells". Biochem. Biophys. Res. Commun. 299 (5): 770–9. doi:10.1016/S0006-291X(02)02720-1. PMID 12470645.
- Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Fan GH, Lapierre LA, Goldenring JR, Sai J, Richmond A (2005). "Rab11-Family Interacting Protein 2 and Myosin Vb Are Required for CXCR2 Recycling and Receptor-mediated Chemotaxis". Mol. Biol. Cell. 15 (5): 2456–69. doi:10.1091/mbc.E03-09-0706. PMC 404037. PMID 15004234.
- Junutula JR, Schonteich E, Wilson GM, Peden AA, Scheller RH, Prekeris R (2004). "Molecular characterization of Rab11 interactions with members of the family of Rab11-interacting proteins". J. Biol. Chem. 279 (32): 33430–7. doi:10.1074/jbc.M404633200. PMID 15173169.
- Lindsay AJ, McCaffrey MW (2005). "The C2 domains of the class I Rab11 family of interacting proteins target recycling vesicles to the plasma membrane". J. Cell Sci. 117 (Pt 19): 4365–75. doi:10.1242/jcs.01280. PMID 15304524. S2CID 7896477.
- Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. Bibcode:2004CBio...14.1436J. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325.
- Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Naslavsky N, Rahajeng J, Sharma M, Jovic M, Caplan S (2006). "Interactions between EHD Proteins and Rab11-FIP2: A Role for EHD3 in Early Endosomal Transport". Mol. Biol. Cell. 17 (1): 163–77. doi:10.1091/mbc.E05-05-0466. PMC 1345656. PMID 16251358.
- Ducharme NA, Hales CM, Lapierre LA, Ham AJ, Oztan A, Apodaca G, Goldenring JR (2006). "MARK2/EMK1/Par-1Bα Phosphorylation of Rab11-Family Interacting Protein 2 Is Necessary for the Timely Establishment of Polarity in Madin-Darby Canine Kidney Cells". Mol. Biol. Cell. 17 (8): 3625–37. doi:10.1091/mbc.E05-08-0736. PMC 1525241. PMID 16775013.
- Ducharme NA, Williams JA, Oztan A, Apodaca G, Lapierre LA, Goldenring JR (2007). "Rab11-FIP2 regulates differentiable steps in transcytosis". Am. J. Physiol., Cell Physiol. 293 (3): C1059–72. doi:10.1152/ajpcell.00078.2007. PMID 17626244. S2CID 34368157.
External links
- Overview of all the structural information available in the PDB for UniProt: Q7L804 (Rab11 family-interacting protein 2) at the PDBe-KB.
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PDB gallery
- 2gzd: Crystal Structure of Rab11 in Complex with Rab11-FIP2
- 2gzh: Crystal Structure of Rab11 in Complex with Rab11-Family Interacting Protein 2
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