Альфа-катенін 1 |
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Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 1H6G, 4EHP, 4IGG | | |
Ідентифікатори |
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Символи | CTNNA1, CAP102, Catenin, MDPT2, catenin alpha 1 |
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Зовнішні ІД | OMIM: 116805 MGI: 88274 HomoloGene: 1433 GeneCards: CTNNA1 |
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Пов'язані генетичні захворювання |
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patterned macular dystrophy 2, patterned macular dystrophy[1] |
Онтологія гена |
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Молекулярна функція | • gamma-catenin binding • actin filament binding • beta-catenin binding • GO:0001948, GO:0016582 protein binding • vinculin binding • structural molecule activity • protein heterodimerization activity • RNA binding • cadherin binding • identical protein binding |
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Клітинна компонента | • Акросома • цитоскелет • внутрішньоклітинна мембранна органела • intercalated disc • actin cytoskeleton • Адгезивні контакти • catenin complex • гіалоплазма • мембрана • клітинна мембрана • цитоплазма • cell-cell junction • міжклітинні контакти • lamellipodium • комплекс Ґольджі • focal adhesion • zonula adherens • flotillin complex |
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Біологічний процес | • positive regulation of smoothened signaling pathway • actin filament organization • response to estrogen • regulation of cell population proliferation • GO:1904578 response to organic cyclic compound • negative regulation of extrinsic apoptotic signaling pathway in absence of ligand • negative regulation of neuroblast proliferation • establishment or maintenance of cell polarity • positive regulation of extrinsic apoptotic signaling pathway in absence of ligand • gap junction assembly • negative regulation of cell motility • negative regulation of integrin-mediated signaling pathway • apical junction assembly • адгезія клітин • GO:0010260 старіння людини • male gonad development • protein heterooligomerization • adherens junction organization • positive regulation of muscle cell differentiation • ovarian follicle development • odontogenesis of dentin-containing tooth • cellular response to indole-3-methanol • negative regulation of apoptotic process • axon regeneration • epithelial cell-cell adhesion |
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Джерела:Amigo / QuickGO | |
Шаблон експресії |
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Більше даних |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | NM_001290307 NM_001290309 NM_001290310 NM_001290312 NM_001903
| NM_001323982 NM_001323983 NM_001323984 NM_001323985 NM_001323986 NM_001323987 NM_001323988 NM_001323989 NM_001323990 NM_001323991 NM_001323992 NM_001323993 NM_001323994 NM_001323995 NM_001323996 NM_001323997 NM_001323998 NM_001323999 NM_001324000 NM_001324001 NM_001324002 NM_001324003 NM_001324004 NM_001324005 NM_001324006 NM_001324007 NM_001324008 NM_001324009 NM_001324010 NM_001324011 NM_001324012 NM_001324013 |
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RefSeq (білок) | NP_001277236 NP_001277238 NP_001277239 NP_001277241 NP_001310911
| NP_001310912 NP_001310913 NP_001310914 NP_001310915 NP_001310916 NP_001310917 NP_001310918 NP_001310919 NP_001310920 NP_001310921 NP_001310922 NP_001310923 NP_001310924 NP_001310925 NP_001310926 NP_001310927 NP_001310928 NP_001310929 NP_001310930 NP_001310931 NP_001310932 NP_001310933 NP_001310934 NP_001310935 NP_001310936 NP_001310937 NP_001310938 NP_001310939 NP_001310940 NP_001310941 NP_001310942 NP_001894 NP_001277236.1 |
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Локус (UCSC) | Хр. 5: 138.61 – 138.94 Mb | Хр. 18: 35.25 – 35.39 Mb |
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PubMed search | [2] | [3] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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