CXCL10 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/4/47/PDB_1o7z_EBI.jpg/250px-PDB_1o7z_EBI.jpg) |
已知的結構 |
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PDB | 直系同源搜索: PDBe RCSB |
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PDBID列表 |
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1O80、1LV9、1O7Y、1O7Z |
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識別號 |
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别名 | CXCL10;, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1, C-X-C motif chemokine ligand 10, C-X-C motif chemokine 10 |
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外部ID | OMIM:147310 MGI:1352450 HomoloGene:1203 GeneCards:CXCL10 |
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基因位置(小鼠) |
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![小鼠5号染色体](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ideogram_house_mouse_chromosome_5.svg/260px-Ideogram_house_mouse_chromosome_5.svg.png) | 染色体 | 小鼠5号染色体[2] |
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| 基因座 | 5 E2|5 46.57 cM | 起始 | 92,494,497 bp[2] |
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终止 | 92,496,748 bp[2] |
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RNA表达模式 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/0/06/PBB_GE_CXCL10_204533_at_fs.png/250px-PBB_GE_CXCL10_204533_at_fs.png) |
查阅更多表达数据 |
基因本體 |
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分子功能 | • 細胞因子活性 • heparin binding • CXCR3 chemokine receptor binding • chemokine activity • 血浆蛋白结合 • cAMP-dependent protein kinase regulator activity • signaling receptor binding • chemoattractant activity
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細胞組分 | • 細胞外區域 • external side of plasma membrane • 細胞外空間 • 胞內
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生物學過程 | • regulation of endothelial tube morphogenesis • negative regulation of myoblast differentiation • cellular response to heat • response to vitamin D • positive regulation of cell migration • T cell chemotaxis • chemokine-mediated signaling pathway • cell-cell signaling • response to virus • muscle organ development • positive regulation of monocyte chemotaxis • positive regulation of release of sequestered calcium ion into cytosol • endothelial cell activation • positive regulation of cAMP-mediated signaling • regulation of T cell chemotaxis • blood circulation • 趨化性 • positive regulation of leukocyte chemotaxis • cell surface receptor signaling pathway • response to lipopolysaccharide • negative regulation of myoblast fusion • defense response to virus • regulation of cell population proliferation • 免疫反应 • positive regulation of cell population proliferation • response to auditory stimulus • negative regulation of angiogenesis • response to cold • cellular response to lipopolysaccharide • response to gamma radiation • positive regulation of T cell migration • 訊息傳遞 • positive regulation of transcription by RNA polymerase II • regulation of protein kinase activity • defense response • inflammatory response • antimicrobial humoral immune response mediated by antimicrobial peptide • regulation of signaling receptor activity • G protein-coupled receptor signaling pathway • cytokine-mediated signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • response to bacterium • neutrophil chemotaxis • leukocyte chemotaxis • positive chemotaxis • regulation of apoptotic process
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Sources:Amigo / QuickGO |
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直系同源 |
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物種 | 人類 | 小鼠 |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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mRNA序列 | | |
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蛋白序列 | | |
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基因位置(UCSC) | Chr 4: 76.02 – 76.02 Mb | Chr 5: 92.49 – 92.5 Mb |
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PubMed查找 | [3] | [4] |
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維基數據 |
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