Formil peptidni receptor 3
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Formil peptidni receptor 3 | |||||||||||
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Identifikatori | |||||||||||
Simboli | FPR3; FPRL2; FMLPY; RMLP-R-I | ||||||||||
Vanjski ID | OMIM: 136539 MGI: 1194495 HomoloGene: 40605 IUPHAR: FPR3 GeneCards: FPR3 Gene | ||||||||||
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Pregled RNK izražavanja | |||||||||||
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podaci | |||||||||||
Ortolozi | |||||||||||
Vrsta | Čovek | Miš | |||||||||
Entrez | 2359 | 14294 | |||||||||
Ensembl | ENSG00000187474 | ENSMUSG00000079700 | |||||||||
UniProt | P25089 | O08790 | |||||||||
RefSeq (mRNA) | NM_002030 | NM_008042 | |||||||||
RefSeq (protein) | NP_002021 | NP_032068 | |||||||||
Lokacija (UCSC) | Chr 19: 56.99 - 57.02 Mb | Chr 17: 18.02 - 18.11 Mb | |||||||||
PubMed pretraga | [1] | [2] |
N-formil peptidni receptor 3 je protein koji je kod ljudi kodiran FPR3 genom.[1][2][3]
Povezano
- Formil peptidni receptor
Literatura
- ↑ Bao L, Gerard NP, Eddy RL Jr, Shows TB, Gerard C (Jul 1992). „Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19”. Genomics 13 (2): 437–40. DOI:10.1016/0888-7543(92)90265-T. PMID 1612600.
- ↑ Durstin M, Gao JL, Tiffany HL, McDermott D, Murphy PM (Jun 1994). „Differential expression of members of the N-formylpeptide receptor gene cluster in human phagocytes”. Biochem Biophys Res Commun 201 (1): 174–9. DOI:10.1006/bbrc.1994.1685. PMID 8198572.
- ↑ „Entrez Gene: FPRL2 formyl peptide receptor-like 2”.
Dodatna literatura
- Christophe T, Karlsson A, Dugave C, et al. (2001). „The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2.”. J. Biol. Chem. 276 (24): 21585–93. DOI:10.1074/jbc.M007769200. PMID 11285256.
- Yang D, Chen Q, Gertz B, et al. (2002). „Human dendritic cells express functional formyl peptide receptor-like-2 (FPRL2) throughout maturation.”. J. Leukoc. Biol. 72 (3): 598–607. PMID 12223529.
- Christophe T, Karlsson A, Rabiet MJ, et al. (2002). „Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4.”. Scand. J. Immunol. 56 (5): 470–6. DOI:10.1046/j.1365-3083.2002.01149.x. PMID 12410796.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs.”. Nat. Genet. 36 (1): 40–5. DOI:10.1038/ng1285. PMID 14702039.
- Ernst S, Lange C, Wilbers A, et al. (2004). „An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family.”. J. Immunol. 172 (12): 7669–76. PMID 15187149.
- Harada M, Habata Y, Hosoya M, et al. (2004). „N-Formylated humanin activates both formyl peptide receptor-like 1 and 2.”. Biochem. Biophys. Res. Commun. 324 (1): 255–61. DOI:10.1016/j.bbrc.2004.09.046. PMID 15465011.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Kang HK, Lee HY, Kim MK, et al. (2005). „The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met inhibits human monocyte-derived dendritic cell maturation via formyl peptide receptor and formyl peptide receptor-like 2.”. J. Immunol. 175 (2): 685–92. PMID 16002663.
- Lee HY, Lee SY, Shin EH, et al. (2007). „F2L, a peptide derived from heme-binding protein, inhibits formyl peptide receptor-mediated signaling.”. Biochem. Biophys. Res. Commun. 359 (4): 985–90. DOI:10.1016/j.bbrc.2007.06.001. PMID 17577578.
Spoljašnje veze
- „Formylpeptide Receptors: FPRL2”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2015-05-18.
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Drugi | Moždano specifični angiogenezni inhibitor (1, 2, 3) • Cadherin (1, 2, 3) • Kalcitonin • CALCRL • CD97 • Kortikotropin-oslobađajući hormon (1, 2) • EMR (1, 2, 3) • Glukagon (GR, GIPR, GLP1R, GLP2R) • Hormon rasta oslobađajući hormon • PACAPR1 • GPR • Latrofilin (1, 2, 3, ELTD1) • Metuselah-slični proteini • Paratiroidni hormon (1, 2) • Sekretin • Vazoaktivni intestinalni peptid (1, 2) |
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glutamat / feromon
Drugi |
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Frizzled / Zaglađeni
Uvojiti | |
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Zaglađeni |
B trdu: peptidi (nrpl/grfl/cytl/horl), receptori (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd, signalni putevi (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)