RXFP3
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Relaksinu/insulinu-slična familija, peptidni receptor 4 | |||||||||||
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Identifikatori | |||||||||||
Simboli | RXFP3; GPCR135; MGC141998; MGC142000; RLN3R1; SALPR | ||||||||||
Vanjski ID | OMIM: 609445 MGI: 2441827 HomoloGene: 9568 IUPHAR: RXFP3 GeneCards: RXFP3 Gene | ||||||||||
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Pregled RNK izražavanja | |||||||||||
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Ortolozi | |||||||||||
Vrsta | Čovek | Miš | |||||||||
Entrez | 51289 | 239336 | |||||||||
Ensembl | ENSG00000182631 | ENSMUSG00000060735 | |||||||||
UniProt | Q9NSD7 | Q5Y988 | |||||||||
RefSeq (mRNA) | NM_016568 | NM_178717 | |||||||||
RefSeq (protein) | NP_057652 | NP_848832 | |||||||||
Lokacija (UCSC) | Chr 5: 33.97 - 33.97 Mb | Chr 15: 10.98 - 10.98 Mb | |||||||||
PubMed pretraga | [1] | [2] |
RXFP3, relaksinu/insulinu-slična familija, peptidni receptor 3, je humani G-protein spregnuti receptor.[1]
Povezano
- Relaksinski receptor
Referfence
- ↑ „Entrez Gene: RXFP3 relaxin/insulin-like family peptide receptor 3”.
Literatura
- Bathgate RA, Ivell R, Sanborn BM, et al. (2005). „Receptors for relaxin family peptides.”. Ann. N. Y. Acad. Sci. 1041: 61–76. DOI:10.1196/annals.1282.010. PMID 15956688.
- Bathgate RA, Ivell R, Sanborn BM, et al. (2006). „International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides.”. Pharmacol. Rev. 58 (1): 7–31. DOI:10.1124/pr.58.1.9. PMID 16507880.
- Matsumoto M, Kamohara M, Sugimoto T, et al. (2000). „The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors.”. Gene 248 (1-2): 183–9. DOI:10.1016/S0378-1119(00)00123-2. PMID 10806363.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Liu C, Eriste E, Sutton S, et al. (2004). „Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135.”. J. Biol. Chem. 278 (50): 50754–64. DOI:10.1074/jbc.M308995200. PMID 14522968.
- Liu C, Chen J, Kuei C, et al. (2005). „Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7.”. Mol. Pharmacol. 67 (1): 231–40. DOI:10.1124/mol.104.006700. PMID 15465925.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Van der Westhuizen ET, Sexton PM, Bathgate RA, Summers RJ (2005). „Responses of GPCR135 to human gene 3 (H3) relaxin in CHO-K1 cells determined by microphysiometry.”. Ann. N. Y. Acad. Sci. 1041: 332–7. DOI:10.1196/annals.1282.053. PMID 15956730.
Spoljašnje veze
- „Relaxin Family Peptide Receptors: RXFP3”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2016-03-03.
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Drugi | Moždano specifični angiogenezni inhibitor (1, 2, 3) • Cadherin (1, 2, 3) • Kalcitonin • CALCRL • CD97 • Kortikotropin-oslobađajući hormon (1, 2) • EMR (1, 2, 3) • Glukagon (GR, GIPR, GLP1R, GLP2R) • Hormon rasta oslobađajući hormon • PACAPR1 • GPR • Latrofilin (1, 2, 3, ELTD1) • Metuselah-slični proteini • Paratiroidni hormon (1, 2) • Sekretin • Vazoaktivni intestinalni peptid (1, 2) |
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glutamat / feromon
Drugi |
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Frizzled / Zaglađeni
Uvojiti | |
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Zaglađeni |
B trdu: peptidi (nrpl/grfl/cytl/horl), receptori (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd, signalni putevi (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)