GPR65
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G protein-spregnuti receptor 65 | |||||||||||
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Identifikatori | |||||||||||
Simboli | GPR65; TDAG8; hTDAG8 | ||||||||||
Vanjski ID | OMIM: 604620 MGI: 108031 HomoloGene: 2675 IUPHAR: GPR65 GeneCards: GPR65 Gene | ||||||||||
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Pregled RNK izražavanja | |||||||||||
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podaci | |||||||||||
Ortolozi | |||||||||||
Vrsta | Čovek | Miš | |||||||||
Entrez | 8477 | 14744 | |||||||||
Ensembl | ENSG00000140030 | ENSMUSG00000021886 | |||||||||
UniProt | Q8IYL9 | Q3UQ35 | |||||||||
RefSeq (mRNA) | NM_003608 | NM_008152 | |||||||||
RefSeq (protein) | NP_003599 | NP_032178 | |||||||||
Lokacija (UCSC) | Chr 14: 87.54 - 87.55 Mb | Chr 12: 98.67 - 98.68 Mb | |||||||||
PubMed pretraga | [1] | [2] |
GPR65, G protein-spregnuti receptor 65, ili psihozinski receptor, je protein koji je kod čoveka kodiran GPR65 genom.[1][2]
Povezano
Literatura
Dodatna literatura
- Im DS, Heise CE, Nguyen T, et al. (2001). „Identification of a molecular target of psychosine and its role in globoid cell formation.”. J. Cell Biol. 153 (2): 429–34. DOI:10.1083/jcb.153.2.429. PMC 2169470. PMID 11309421.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Heilig R, Eckenberg R, Petit JL, et al. (2003). „The DNA sequence and analysis of human chromosome 14.”. Nature 421 (6923): 601–7. DOI:10.1038/nature01348. PMID 12508121.
- Sin WC, Zhang Y, Zhong W, et al. (2004). „G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers.”. Oncogene 23 (37): 6299–303. DOI:10.1038/sj.onc.1207838. PMID 15221007.
- Wang JQ, Kon J, Mogi C, et al. (2004). „TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor.”. J. Biol. Chem. 279 (44): 45626–33. DOI:10.1074/jbc.M406966200. PMID 15326175.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ishii S, Kihara Y, Shimizu T (2005). „Identification of T cell death-associated gene 8 (TDAG8) as a novel acid sensing G-protein-coupled receptor.”. J. Biol. Chem. 280 (10): 9083–7. DOI:10.1074/jbc.M407832200. PMID 15618224.
- Radu CG, Nijagal A, McLaughlin J, et al. (2005). „Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells.”. Proc. Natl. Acad. Sci. U.S.A. 102 (5): 1632–7. DOI:10.1073/pnas.0409415102. PMC 545089. PMID 15665078.
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Drugi | Moždano specifični angiogenezni inhibitor (1, 2, 3) • Cadherin (1, 2, 3) • Kalcitonin • CALCRL • CD97 • Kortikotropin-oslobađajući hormon (1, 2) • EMR (1, 2, 3) • Glukagon (GR, GIPR, GLP1R, GLP2R) • Hormon rasta oslobađajući hormon • PACAPR1 • GPR • Latrofilin (1, 2, 3, ELTD1) • Metuselah-slični proteini • Paratiroidni hormon (1, 2) • Sekretin • Vazoaktivni intestinalni peptid (1, 2) |
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glutamat / feromon
Drugi |
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Frizzled / Zaglađeni
Uvojiti | |
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Zaglađeni |
B trdu: peptidi (nrpl/grfl/cytl/horl), receptori (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd, signalni putevi (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)