TAAR8
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Trag amin-asocirani receptor 8 | |||||||||||
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Identifikatori | |||||||||||
Simboli | TAAR8; GPR102; TA5; TAR5; TRAR5; TaR-5; TaR-8 | ||||||||||
Vanjski ID | OMIM: 606927 MGI: 2685076 HomoloGene: 77586 IUPHAR: TAAR8 GeneCards: TAAR8 Gene | ||||||||||
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Pregled RNK izražavanja | |||||||||||
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podaci | |||||||||||
Ortolozi | |||||||||||
Vrsta | Čovek | Miš | |||||||||
Entrez | 83551 | 215859 | |||||||||
Ensembl | ENSG00000146385 | ENSMUSG00000050804 | |||||||||
UniProt | Q969N4 | Q5QD07 | |||||||||
RefSeq (mRNA) | NM_053278.1 | NM_001010830.1 | |||||||||
RefSeq (protein) | NP_444508.1 | NP_001010830.1 | |||||||||
Lokacija (UCSC) | Chr 6: 132.87 - 132.87 Mb | Chr 10: 23.8 - 23.8 Mb | |||||||||
PubMed pretraga | [1] | [2] |
Trag amin-asocirani receptor 8 je protein koji je kod ljudi kodiran TAAR8 genom.[1][2][3]
G protein spregnuti receptori sadrže 7 transmembranskih domena i prenose ekstracelularne signale kroz putem heterotrimerinih G proteina.[3]
Povezano
- Trag amin-asocirani receptor
Reference
- ↑ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). „Discovery and mapping of ten novel G protein-coupled receptor genes”. Gene 275 (1): 83–91. DOI:10.1016/S0378-1119(01)00651-5. PMID 11574155.
- ↑ Lindemann L, Ebeling M, Kratochwil NA, Bunzow JR, Grandy DK, Hoener MC (Feb 2005). „Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors”. Genomics 85 (3): 372–85. DOI:10.1016/j.ygeno.2004.11.010. PMID 15718104.
- ↑ 3,0 3,1 „Entrez Gene: TAAR8 trace amine associated receptor 8”.
Literatura
- Borowsky B, Adham N, Jones KA, et al. (2001). „Trace amines: identification of a family of mammalian G protein-coupled receptors.”. Proc. Natl. Acad. Sci. U.S.A. 98 (16): 8966–71. DOI:10.1073/pnas.151105198. PMC 55357. PMID 11459929.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). „The DNA sequence and analysis of human chromosome 6.”. Nature 425 (6960): 805–11. DOI:10.1038/nature02055. PMID 14574404.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
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Drugi | Moždano specifični angiogenezni inhibitor (1, 2, 3) • Cadherin (1, 2, 3) • Kalcitonin • CALCRL • CD97 • Kortikotropin-oslobađajući hormon (1, 2) • EMR (1, 2, 3) • Glukagon (GR, GIPR, GLP1R, GLP2R) • Hormon rasta oslobađajući hormon • PACAPR1 • GPR • Latrofilin (1, 2, 3, ELTD1) • Metuselah-slični proteini • Paratiroidni hormon (1, 2) • Sekretin • Vazoaktivni intestinalni peptid (1, 2) |
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glutamat / feromon
Drugi |
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Frizzled / Zaglađeni
Uvojiti | |
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Zaglađeni |
B trdu: peptidi (nrpl/grfl/cytl/horl), receptori (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd, signalni putevi (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)