Neuropeptidni FF receptor 2
edit |
Neuropeptidni FF receptor 2 | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Identifikatori | |||||||||||
Simboli | NPFFR2; GPR74; NPFF2; NPGPR | ||||||||||
Vanjski ID | OMIM: 607449 MGI: 1860130 HomoloGene: 56982 IUPHAR: NPFF2 GeneCards: NPFFR2 Gene | ||||||||||
| |||||||||||
Ortolozi | |||||||||||
Vrsta | Čovek | Miš | |||||||||
Entrez | 10886 | 104443 | |||||||||
Ensembl | ENSG00000056291 | ENSMUSG00000035528 | |||||||||
UniProt | Q9Y5X5 | Q924N0 | |||||||||
RefSeq (mRNA) | NM_004885 | XM_973847 | |||||||||
RefSeq (protein) | NP_004876 | XP_978941 | |||||||||
Lokacija (UCSC) | Chr 4: 73.12 - 73.23 Mb | Chr 5: 90.6 - 90.66 Mb | |||||||||
PubMed pretraga | [1] | [2] |
Neuropeptidni FF receptor 2 (NPFF2) je humani protein kodiran NPFFR2 genom.[1]
Povezano
- Neuropeptidni FF receptor
Reference
- ↑ „Entrez Gene: NPFFR2 neuropeptide FF receptor 2”.
Literatura
- Cikos S, Gregor P, Koppel J (1999). „Sequence and tissue distribution of a novel G-protein-coupled receptor expressed prominently in human placenta.”. Biochem. Biophys. Res. Commun. 256 (2): 352–6. DOI:10.1006/bbrc.1999.0332. PMID 10079187.
- Parker RM, Copeland NG, Eyre HJ, et al. (2000). „Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family.”. Brain Res. Mol. Brain Res. 77 (2): 199–208. DOI:10.1016/S0169-328X(00)00052-8. PMID 10837915.
- Elshourbagy NA, Ames RS, Fitzgerald LR, et al. (2000). „Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor.”. J. Biol. Chem. 275 (34): 25965–71. DOI:10.1074/jbc.M004515200. PMID 10851242.
- Bonini JA, Jones KA, Adham N, et al. (2001). „Identification and characterization of two G protein-coupled receptors for neuropeptide FF.”. J. Biol. Chem. 275 (50): 39324–31. DOI:10.1074/jbc.M004385200. PMID 11024015.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Laemmle B, Schindler M, Beilmann M, et al. (2003). „Characterization of the NPGP receptor and identification of a novel short mRNA isoform in human hypothalamus.”. Regul. Pept. 111 (1–3): 21–9. DOI:10.1016/S0167-0115(02)00220-3. PMID 12609745.
- Engström M, Wurster S, Savola JM, Panula P (2004). „Functional properties of Pfr(Tic)amide and BIBP3226 at human neuropeptide FF2 receptors”. Peptides 24 (12): 1947–54. DOI:10.1016/j.peptides.2003.10.009. PMID 15127947.
- Mollereau C, Mazarguil H, Zajac JM, Roumy M (2005). „Neuropeptide FF (NPFF) analogs functionally antagonize opioid activities in NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells”. Mol. Pharmacol. 67 (3): 965–75. DOI:10.1124/mol.104.004614. PMID 15608144.
- Ankö ML, Panula P (2006). „Regulation of endogenous human NPFF2 receptor by neuropeptide FF in SK-N-MC neuroblastoma cell line”. J. Neurochem. 96 (2): 573–84. DOI:10.1111/j.1471-4159.2005.03581.x. PMID 16336216.
- Ankö ML, Ostergård M, Lintunen M, Panula P (2007). „Alternative splicing of human and mouse NPFF2 receptor genes: Implications to receptor expression”. FEBS Lett. 580 (30): 6955–60. DOI:10.1016/j.febslet.2006.11.063. PMID 17157836.
- Dahlman I, Dicker A, Jiao H, et al. (2007). „A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis”. Am. J. Hum. Genet. 80 (6): 1115–24. DOI:10.1086/518445. PMC 1867099. PMID 17503329.
Spoljašnje veze
- „Neuropeptide FF Receptors: NPFF2”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2016-03-03.
- p
- r
- u
Drugi | Moždano specifični angiogenezni inhibitor (1, 2, 3) • Cadherin (1, 2, 3) • Kalcitonin • CALCRL • CD97 • Kortikotropin-oslobađajući hormon (1, 2) • EMR (1, 2, 3) • Glukagon (GR, GIPR, GLP1R, GLP2R) • Hormon rasta oslobađajući hormon • PACAPR1 • GPR • Latrofilin (1, 2, 3, ELTD1) • Metuselah-slični proteini • Paratiroidni hormon (1, 2) • Sekretin • Vazoaktivni intestinalni peptid (1, 2) |
---|
glutamat / feromon
Drugi |
---|
Frizzled / Zaglađeni
Uvojiti | |
---|---|
Zaglađeni |
B trdu: peptidi (nrpl/grfl/cytl/horl), receptori (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd, signalni putevi (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)